Wearable laser Doppler based on VCSEL and its application in human blood flow

Hualiang Zhang, Jinjiang Cui, Xiaoman Xing, Jian-gen Xu
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Abstract

A wearable microcirculation detection device based on VCSEL with high optical speed vertical cavity surface emission laser chip and three-axis acceleration sensor were used in the continuous detection experiment of human microcirculation .20 people of different ages were tested reactive hyperemia of fingers under different pressures on the upper arm(The experiment was divided into two groups. In the first group we continuously changed the pressure, increased the pressure from 0mmHg to 180mmHg. When the pressure reached 0, 100, 150, 180mmHg, the constant pressures was maintained for 1 minute respectively to observe blood flow waveform. In the second group we directly increased the pressure to 180mmHg, and then released the pressure after 3 minutes.). Test results indicate that; Blood flow changed more slowly when the pressure was 0mmHg to 100mmHg. From 100mmHg to 150mmHg, the blood flow had a pulsating waveform with the heart beating, and the blood flow decreased gradually. From 150mmHg to 180mmHg, blood flow varied greatly and decreased to a minimum after the pressure reached 180mmHg and did not change significantly as the pressure increased. When the pressure was released, the Blood flow rose rapidly from the lowest to a peak and then gradually returned to normal state. Compared with young people under 30 years old, the blood flow of the elderly recovered more slowly, and the peak of the blood flow was lower than that of the young. The two groups of experiments can distinguish the difference of age.
基于VCSEL的可穿戴激光多普勒及其在人体血流中的应用
采用基于VCSEL的可穿戴式微循环检测装置,结合高光速垂直腔面发射激光芯片和三轴加速度传感器对人体微循环进行连续检测实验,测试20名不同年龄的人在上臂不同压力下手指反应性充血(实验分为两组)。在第一组中,我们不断改变压力,将压力从0mmHg增加到180mmHg。在血压达到0、100、150、180mmHg时,分别保持恒压1分钟,观察血流波形。第二组直接加压至180mmHg, 3分钟后放压)。试验结果表明:在0 ~ 100mmHg血压范围内,血流变化较慢。从100mmHg到150mmHg,血流随心脏跳动呈脉动波形,血流逐渐减少。从150mmHg到180mmHg,血流量变化较大,在180mmHg后降至最小,随着血压的升高,血流量变化不明显。当压力释放后,血流量从最低迅速上升到峰值,然后逐渐恢复正常状态。与30岁以下的年轻人相比,老年人的血流量恢复更慢,血流量峰值低于年轻人。两组实验可以区分年龄的差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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