Association and Outcome of ABO-Rh Blood Group among 294 COVID-19 Patients admitted in A Dedicated Hospital

Journal of Medical Science & Research Pub Date : 2022-01-01 DOI:10.47648/jmsr.2022.v3201.01

Perveen RA, Nasir M, Pervin S, Zahan T, Farha N

{"title":"Association and Outcome of ABO-Rh Blood Group among 294 COVID-19 Patients admitted in A Dedicated Hospital","authors":"Perveen RA, Nasir M, Pervin S, Zahan T, Farha N","doi":"10.47648/jmsr.2022.v3201.01","DOIUrl":null,"url":null,"abstract":"Aim: The rapid global spread of the novel corona virus SARS-CoV-2 has strained healthcare and testing resources, making the identification and prioritization of individuals most at-risk became a critical challenge. Recent evidence suggests blood type may affect the risk of severe COVID-19.Method: In this cross-sectional observational study, among 1348 admitted patients in Holy Family Red Crescent Medical College who tested positive for RT-PCR, 294 patients were included with known blood type to assess the association between ABO and Rh blood types and demographic profile, co-morbidities, clinical outcomes, and changes in the biomarkers. Result: among 294 patients admitted to the hospital with COVID-19, the mean age was 48 to 49 years. Out of all patients, 211 were male, and 83 were female, with a ratio of 1: 2.54. The highest numbers of patients were between 50-59 years. The highest percentage of diabetic patients were present in the AB blood group (54%), and hypertensive patients in the O and Rh-negative blood group (40.29%, 60%) which were statistically not significant. Other than that, COPD, IHD, and CKD were observed. Symptoms of patients were categorized as inflammatory and neurological. Shortness of breath (52.41%), fever (38.43%), and cough (28.23%) were observed among inflammatory symptoms, which were statistically significant and lethargy (16.25%) was only remarkable neurological involvement. Among all ABO blood groups, 'A' blood group of patients, present with a higher percentage of both inflammatory and neurological symptoms. Among the Rh blood group, Rh-negative patients did not present with diarrhea, sore throat, lethargy, anosmia, and loss of taste. Changes in biomarkers levels were also observed in all blood groups. Conclusion: COVID-19 patients with blood group A or B are at increased risk of disease severity with the highest number of co morbidities and symptoms compared with patients with blood group O or AB.","PeriodicalId":315974,"journal":{"name":"Journal of Medical Science & Research","volume":"3 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Medical Science & Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.47648/jmsr.2022.v3201.01","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Aim: The rapid global spread of the novel corona virus SARS-CoV-2 has strained healthcare and testing resources, making the identification and prioritization of individuals most at-risk became a critical challenge. Recent evidence suggests blood type may affect the risk of severe COVID-19.Method: In this cross-sectional observational study, among 1348 admitted patients in Holy Family Red Crescent Medical College who tested positive for RT-PCR, 294 patients were included with known blood type to assess the association between ABO and Rh blood types and demographic profile, co-morbidities, clinical outcomes, and changes in the biomarkers. Result: among 294 patients admitted to the hospital with COVID-19, the mean age was 48 to 49 years. Out of all patients, 211 were male, and 83 were female, with a ratio of 1: 2.54. The highest numbers of patients were between 50-59 years. The highest percentage of diabetic patients were present in the AB blood group (54%), and hypertensive patients in the O and Rh-negative blood group (40.29%, 60%) which were statistically not significant. Other than that, COPD, IHD, and CKD were observed. Symptoms of patients were categorized as inflammatory and neurological. Shortness of breath (52.41%), fever (38.43%), and cough (28.23%) were observed among inflammatory symptoms, which were statistically significant and lethargy (16.25%) was only remarkable neurological involvement. Among all ABO blood groups, 'A' blood group of patients, present with a higher percentage of both inflammatory and neurological symptoms. Among the Rh blood group, Rh-negative patients did not present with diarrhea, sore throat, lethargy, anosmia, and loss of taste. Changes in biomarkers levels were also observed in all blood groups. Conclusion: COVID-19 patients with blood group A or B are at increased risk of disease severity with the highest number of co morbidities and symptoms compared with patients with blood group O or AB.

查看原文本刊更多论文

某专科医院294例新冠肺炎患者ABO-Rh血型与预后的关系

目的:新型冠状病毒SARS-CoV-2在全球范围内的快速传播使医疗和检测资源紧张，使最危险个体的识别和优先排序成为一项关键挑战。最近的证据表明，血型可能会影响严重COVID-19的风险。方法:在这项横断面观察性研究中，在圣家红新月医学院1348例RT-PCR检测阳性的入院患者中，纳入294例已知血型的患者，以评估ABO和Rh血型与人口统计学特征、合并症、临床结局和生物标志物变化之间的关系。结果:294例新冠肺炎住院患者，平均年龄48 ~ 49岁。男性211例，女性83例，男女比例为1:2.54。患者最多的年龄在50-59岁之间。AB血型的糖尿病患者比例最高(54%)，O和rh阴性血型的高血压患者比例最高(40.29%，60%)，差异均无统计学意义。此外，观察COPD、IHD、CKD。患者症状分为炎症性和神经性。炎症症状中呼吸短促(52.41%)、发热(38.43%)、咳嗽(28.23%)均有统计学意义，而嗜睡(16.25%)仅明显累及神经系统。在所有ABO血型中，A血型患者出现炎症和神经系统症状的比例较高。在Rh血型中，Rh阴性患者没有出现腹泻、喉咙痛、嗜睡、嗅觉丧失和味觉丧失。在所有血型中也观察到生物标志物水平的变化。结论:与O型或AB型患者相比，A型或B型患者疾病严重程度风险增加，合并症和症状数量最多。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of Medical Science & Research

自引率

0.00%

发文量