Medication safety in elderly patients

A. Ahuja
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Abstract

The present manuscript describes health problems that commonly affect elderly patients and explain which and why some drugs increase the risk of having problems related to drugs. The physiological changes that occur with ageing and how these impact on drug therapy are also explained. A brief detail of drugs that commonly cause adverse drug reactions (ADR’s) are covered along with a plan for preventing them and improving the quality of life. compensatory mechanisms (homeostasis). Postural hypotension results from impaired baroreceptor function reduced compensatory tachycardia and vasoconstriction in response to hypotension and failure of cerebral blood flow autoregulation. Patients with impaired cardiac output and taking diuretics are especially vulnerable.
老年患者用药安全
本手稿描述了通常影响老年患者的健康问题,并解释了哪些以及为什么某些药物会增加与药物有关的问题的风险。随着年龄的增长而发生的生理变化以及这些变化对药物治疗的影响也得到了解释。简要介绍了通常引起药物不良反应(ADR)的药物,以及预防它们和改善生活质量的计划。补偿机制(体内平衡)。体位性低血压是由于压力感受器功能受损、代偿性心动过速减少和血管收缩引起的低血压和脑血流自动调节失败。心排血量受损和服用利尿剂的患者尤其容易受到影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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