Impact of Marijuana Smoking on Lung Health

D. Tashkin
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Abstract

This chapter reviews the literature pertaining to the concern that regular smoking of marijuana contributes to the well-known respiratory consequences of regular tobacco smoking, including, chronic obstructive pulmonary disease (COPD) and respiratory cancer. Whereas regular marijuana smoking is associated with symptoms of acute and chronic bronchitis and evidence of microscopic injury to the cells lining the central airways, the majority of community- or population-based studies in regular smokers of marijuana have not found evidence of clinically significant impairment in lung function in comparison with nonsmokers that would be consistent with COPD. However, very few studies have been conducted in older marijuana smokers in the age range when COPD is generally diagnosed, and few longitudinal studies of change in lung function over time have been carried out in smokers of marijuana. Therefore, firm conclusions regarding the potential risks of marijuana for the development of COPD must await additional studies.
吸食大麻对肺部健康的影响
本章回顾了有关经常吸食大麻会导致众所周知的经常吸烟的呼吸系统后果的文献,包括慢性阻塞性肺疾病(COPD)和呼吸系统癌症。尽管经常吸食大麻与急性和慢性支气管炎的症状有关,并有证据表明对中央气道内衬细胞有显微损伤,但大多数以社区或人群为基础的研究发现,与不吸烟者相比,经常吸食大麻的人没有发现肺功能有临床显著损害的证据,这与慢性阻塞性肺病是一致的。然而,很少有研究对COPD一般诊断年龄范围内的老年大麻吸食者进行,也很少有对大麻吸食者肺功能随时间变化的纵向研究。因此,关于大麻对慢性阻塞性肺病发展的潜在风险的确切结论必须等待进一步的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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