Diuretic intervention improves accuracy of 18F-fluorodeoxyglucose PET-CT in bladder malignancies

Abstract

18F Fluorodeoxyglucose 18F-FDG, positron emission tomography computed tomography (PET-CT) is a relatively new imaging modality which is increasingly being used in the diagnosis and management of patients suffering with different types of cancer in body. 18FDG tracer molecule, clears from body through urinary tract. Physiological presence of tracer activity in urinary bladder (UB) at the time of scanning may be a limitation for appropriate evaluation of patients suffering with UB cancer.1 To overcome this limitation some investigators suggested the utility of a delayed scan after diuretic intervention to improve the diagnostic sensitivity of the test in this group of patients.2,3