A Case Report of Multibacillary Leprosy Presenting with Multiple Outbreaks of Erythema Nodosum Leprosum

R. Bouceiro-Mendes, A. Ortins-Pina, T. Marques, M. Viveiros, D. Machado, L. Lito, J. Ferreira, L. Soares-de-Almeida, J. Freitas, P. Filipe
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Abstract

Leprosy is a chronic granulomatous disease with a long incubation period caused by Mycobacterium leprae that mainly affects the skin, mucous membranes and the peripheral nervous system. It carries the risk of per-manent sequels with a significant impact on the patient’s quality of life. It has a considerable clinically diver-sity and possible atypical presentations. We present a case of a 31-year-old, skin phototype V woman with multibacillary leprosy characterized by multiple outbreaks of erythema nodosum leprosum, as an inaugural manifestation of the disease. The disease was acquired within a group of children and adolescents from an endemic region of Africa, evolved untreated for 3 years, and presented with unusual features and remarkable lymphatic involvement. We highlight the importance of building and maintaining collaboration between expert centers and institutional partnerships in order to provide the adequate diagnostic resources and appropriate care to the affected populations.
多菌性麻风1例,并发多发麻风结节性红斑
麻风是由麻风分枝杆菌引起的一种潜伏期较长的慢性肉芽肿性疾病,主要累及皮肤、粘膜和周围神经系统。它具有永久性后遗症的风险,对患者的生活质量有重大影响。它具有相当大的临床多样性和可能的非典型表现。我们提出一个31岁的病例,皮肤光型V型妇女多菌性麻风病的特点是多次爆发的麻风结节性红斑,作为该疾病的首次表现。该疾病是在非洲一个流行地区的一组儿童和青少年中获得的,在未经治疗的情况下发展了3年,呈现出不寻常的特征和明显的淋巴受累。我们强调在专家中心和机构伙伴关系之间建立和保持合作的重要性,以便为受影响的人群提供充分的诊断资源和适当的护理。
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