A study of clinical and laboratory profile of UTI in diabetics in Sir T. Hospital, Bhavnagar — observnational cross-sectional study

Abstract

Diabetes Mellitus (DM) is a chronic metabolic disorder characterized by hyperglycaemia caused by defects in insulin secretion, action, or both. Immune dysfunction is a major issue in the disease course, and it can manifest as either autoimmune disease or a poor immune response, the latter of which leads to a higher incidence of infections. The link between a higher incidence of urinary tract infections (UTI) and diabetes has been attributed to immune system impairments, poor metabolic control, and incomplete bladder emptying due to autonomic neuropathy. Poor glycaemic control may predispose to more severe UTI and greatly increase the risk of complications in UTI.200 diabetic patients were screened for UTI admitted at Sir T. General Hospital, Bhavnagar over the period of 6 months from 1st November 2021 to 30 the April.2022. The various measures of central tendencies and graphical representations were used to analyse the data.Majority subjects were from age group of 46 – 60 years 74 (37%) followed by 31-45 years 59 (29.5%), > 60 years was 44 (22%) and 18-30 years was 23 (11.5%) respectively. It was found that female patients 103 (51.5%) marginally higher than male 97 (48.5%). The ratio of male: female was 1:1.06. UTI was found to be significantly associated with advanced age and poorly controlled Diabetes.