[A molecular genetic analysis of the 12th codon of the Ha-ras-1 proto-oncogene in human carcinoma and stomach ulcer cells].

Eksperimental'naia onkologiia Pub Date : 1990-01-01
L B Novikov, S N Fedorov, O S Iatsuk, V P Kalinovskiĭ, N Ia Tlevlesov, G I Levanova, B V Matveev, R A Mel'nikov, I F Seĭts
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引用次数: 0

Abstract

A method of the restriction analysis by Msp I enzyme has been used to analyze the 12th codon of Ha-ras-1 protooncogene in 10 human carcinomas and in the stomach mucosa adjacent to them their 5 metastases into the regional lymph nodes and in 2 ulcers. No point mutation was found.

[人癌和胃溃疡细胞Ha-ras-1原癌基因第12密码子的分子遗传学分析]。
采用Msp I酶限制性内切分析的方法,分析了10例人癌及其邻近胃黏膜的Ha-ras-1原癌基因第12密码子,其中5例转移到局部淋巴结,2例溃疡。未发现点突变。
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