Non-contact Massively Parallel Manipulation of Micro-objects by Optoelectronic Tweezers*

Chunyuan Gan, Shuzhang Liang, Fenghui Wang, Yuqing Cao, Yiming Ji, J. Lina, Li Song, Lin Feng
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引用次数: 3

Abstract

Optoelectronic tweezers (OET) system is a novel platform, by changing the projection pattern it can achieve the real-time precise control of the micro-objects. Due to its outstanding biocompatibility to cells and other biological materials, such as no damage, less heat generation, no contact and other characteristics, it has attracted wide attention in the field of micro-nano robots and micro-operation. Here we present a low power, high precision operation control method which can achieve a large operating range. Firstly, the properties of dielectrophoresis (DEP) force were calculated by using polarization theory and Maxwell stress tensor (MST) method, and the precise control of the single particle of polystyrene beads was completed by transforming and upgrading the projection light path and observation light path and using visual feedback control method. In addition, a custom-designed pattern scheme was used to achieve the rapid aggregation of polystyrene beads in a short time according to the image model and the classification of different particle sizes. This study provides a very effective technical method for precise single particle operation and large-scale parallel operation at micro-nano scale.
基于光电镊子的微物体非接触大规模并行操纵*
光电镊子(OET)系统是一种新颖的平台,通过改变其投影模式来实现对微物体的实时精确控制。由于其对细胞和其他生物材料具有优异的生物相容性,如不损伤、发热少、不接触等特点,在微纳机器人和微操作领域引起了广泛关注。本文提出了一种低功耗、高精度的运行控制方法,可以实现大的运行范围。首先,利用极化理论和麦克斯韦应力张量(MST)方法计算dielectrophoresis (DEP)力的性质,通过对投影光路和观测光路的变换和升级,采用视觉反馈控制方法完成对聚苯乙烯珠粒单粒子的精确控制。此外,根据图像模型和不同粒径的分类,采用定制的图案方案,实现了聚苯乙烯微珠在短时间内的快速聚集。该研究为微纳尺度上的精确单粒子运算和大规模并行运算提供了非常有效的技术手段。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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