Genetically Engineered Probiotics and Therapies Applications

M. C. Stephanie, Jijón V. Santiago
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Abstract

The idea of using probiotics for health benefits in the human body is still biased since there is skepticism and since it is quite a new field of research. However, recent experiments are trying to debate that given the naturality of their consumption and the successful results from in vitro tests in combination with other therapies. Food scientists are eager to take advantage of the known beneficial properties of probiotics by using engineering technologies in order to enhance them. Using CRISPR systems present in lactobacilli aids in strain identification, while offering information on phylogeny and ecological interactions. Also, the use of genetic engineering tools could also allow the use of plasmid vaccines to prevent antibiotic resistance and the development of synthetic probiotics as microbial treatments.
基因工程益生菌及其治疗应用
使用益生菌对人体健康有益的想法仍然存在偏见,因为存在怀疑,因为这是一个相当新的研究领域。然而,最近的实验正在试图争论,鉴于其消费的自然性和体外试验与其他疗法相结合的成功结果。食品科学家渴望利用益生菌已知的有益特性,通过工程技术来增强它们。使用存在于乳酸菌中的CRISPR系统有助于菌株鉴定,同时提供系统发育和生态相互作用的信息。此外,使用基因工程工具还可以使用质粒疫苗来预防抗生素耐药性,并开发合成益生菌作为微生物治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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