Marjolin's Ulcer: Seven (07) Cases Studied in Brazzaville

J. N. Malanda, Sophie Bayonne Kombo, Grâce Dulcinée Mabiala Maye, Augustin Bambara Tozoula, Aubièrge Victoire Kimpamboudi Matondo, E. Ndounga, Jean Bernard Nkoua Mbon
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Abstract

Introduction Marjolin's Ulcer (MU) means all cutaneous malignancies developed on old unsteady scars. The general objective of this study was to report the MU cases in Congo with a literature review. It was a retrospective study conducted at University Teaching Hospital in Brazzaville from January 1998 to December 2017 (a 20-year period). The in-patients for cutaneous cancer histologically confirmed, arose on scarring skin lesions progressive were included. The epidemiological, clinical, histopathological and therapeutical variables were collected. Seven patients were identified. They represented 1.9% of skin cancers. The middle age was 44.4 years. The female predomination was noted with a sex ratio of 2.5. The burn scars was the etiological factor found to all our patients (100%). None of patients had an appropriate care of initial wound. The average time limit of the onset of MU was 34 years. The anatomopathologic examination revealed a squamous cell carcinoma to all our patients (100%). Carcinologic exeresis carried out to one (01) patient (14.28%). The amputation: three (03) patients (42.85%) and the disarticulation: two (02) patients (28.57%). The chemotherapy six (06) patients (85.71%). The decease arose five (05) patients (71.42%) and the entire remission reached to a woman patient (14.28%). This study confirmed the rareness and the severity MU; it also reveals the diagnosis lateness of a great death-rate. The care of quality of burns and chronic injuries, the awareness of patients together with the care givers training could help to improve the prognosis of this affection.
马卓林溃疡:布拉柴维尔7(07)例报告
马卓林溃疡(Marjolin's Ulcer, MU)是指发生在旧的不稳定疤痕上的所有皮肤恶性肿瘤。本研究的总体目的是报告刚果的MU病例并进行文献回顾。这是1998年1月至2017年12月在布拉柴维尔大学教学医院进行的一项回顾性研究(为期20年)。组织学证实为皮肤癌的住院患者,发生在瘢痕性皮肤病变进展。收集流行病学、临床、组织病理学和治疗变量。确定了7例患者。他们占皮肤癌的1.9%。中年为44.4岁。女性占主导地位,性别比例为2.5。所有患者(100%)的病因均为烧伤瘢痕。所有患者均未得到适当的初始伤口护理。MU发病的平均时限为34年。解剖病理检查显示所有患者(100%)为鳞状细胞癌。1例(01例)患者(14.28%)行癌变检查。其中截肢3例(03例),占42.85%;骨折2例(02例),占28.57%。化疗6例(06例),占85.71%。5例(05)例(71.42%)患者死亡,1例女性患者完全缓解(14.28%)。本研究证实了MU的稀缺性和严重性;它也揭示了高死亡率的诊断迟发性。提高烧伤和慢性损伤的护理质量,提高患者的护理意识,并对护理人员进行培训,有助于改善烧伤和慢性损伤的预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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