Association between Steroid Anti-Inflammatory Drugs and Oral-Dental State- A Literature Review

Abstract

It has been established that people accepting oral corticosteroids often suffer from lack of teeth or are characterized with caries-non-resistant dentition. Corticosteroids can affect the consistency of alveolar bone, causing its osteoporotic alteration related to reduction of osteoblasts and amount of osteoid matrix. Parallel to the application of corticosteroids, there is a tendency of decrease of the height of alveolar bone and fibrous transformation of the periodontal space. There can be established severe loss of supporting alveolar bone. Corticosteroids therapy interrelates to enhanced potential for clinical manifestation of alterations of taste sensation, periodontitis, gingivitis, ulceration, candidiasis, tooth decay, xerostomia.