Multiple Sclerosis Clinic in Iraq, an Endeavourforan Unraveling Database

H. Mohammed, M. Kamil, H. Aboud, B. Hassan
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引用次数: 7

Abstract

Multiple sclerosis (MS) is the most common disabling neurologic condition of young adults after trauma. The establishing of an unraveling database carries a potentially important role in clarifying the nature of the disease in Iraq. This study had been designed to find the frequency distribution of MS patients according to different demographic variables like the age at onset, age at diagnosis, gender and place of birth and residence, etc, to estimate the frequency of different neurological symptoms and signs in patients with MS, to estimate the frequency of different clinical types of MS in Iraqi patients and assessing the differences between different clinical types of MS in regard to gender, age at onset, age at diagnosis, the diagnostic delay, disease duration and the EDSS, accordingly. This retrospective study was carried out at the Multiple Sclerosis Clinic, Medical City in Baghdad/lraq. The medical files of 900 MS patients were thoroughly revised; they included all patients who had attended the MS Clinic from the day of establishment of the clinic at 2001 to the end of February 2006. Six hundreds seventy six (676) patients were considered as MS patients fulfilling the Poser's criteria and continued visiting the clinic for follow up and treatment. Patient's distribution according to the clinical type of their MS was RRMS= 67.3%, PPMS= 19.1%, SPMS= 13.6% , main age distribution of this sample was between 30-39 years (39.3%).,Females were 64.9%, males were 35.1%.,Age of onset was mainly between 20-29 years of age regardless of the gender or type of MS, Diagnostic delay was mainly between 1-3 years, Distribution according to place of birth was seen mainly in 3 geographical clusters in Iraq, Motor symptoms were the commonest experienced by the patients (95.7%). This study had shown that during the last 2 decades, MS was increasingly encountered in Iraq, particularly during the last 5 years after the establishment of MS clinic in Baghdad, MS cases in Iraq distributed in a three-main-clusters pattern rather than North-South gradient, primary progressive MS showed a more even gender distribution and older age at onset with the shortest diagnostic delay.
伊拉克多发性硬化症诊所,一个努力解开数据库
多发性硬化症(MS)是年轻人创伤后最常见的致残神经系统疾病。建立一个分析数据库在澄清伊拉克疾病的性质方面具有潜在的重要作用。本研究旨在根据发病年龄、诊断年龄、性别、出生和居住地等不同人口统计学变量,寻找MS患者的频率分布,估计MS患者不同神经系统症状和体征的频率,估计伊拉克MS患者不同临床类型的频率,评估MS不同临床类型在性别、发病年龄、诊断年龄、诊断延迟、病程和EDSS。这项回顾性研究是在伊拉克巴格达医学城多发性硬化症诊所进行的。对900例多发性硬化症患者的医疗档案进行全面修改;包括由MS诊所于2001年成立当日至2006年2月底曾到该诊所就诊的所有病人。676例患者被认为是符合Poser标准的MS患者,并继续到诊所进行随访和治疗。MS临床分型的分布为RRMS= 67.3%, PPMS= 19.1%, SPMS= 13.6%,主要年龄分布在30 ~ 39岁之间(39.3%)。,女性占64.9%,男性占35.1%。发病年龄主要在20 ~ 29岁之间,与性别、类型无关,诊断延迟主要在1 ~ 3年之间,根据出生地分布主要在伊拉克的3个地理聚集群中,运动症状最常见(95.7%)。本研究表明,近20年来,MS在伊拉克越来越多地出现,特别是在巴格达建立MS诊所后的近5年,伊拉克MS病例呈三主聚集型分布,而不是南北梯度分布,原发性进展性MS性别分布更均匀,发病年龄更大,诊断延迟最短。
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