Correlation of Neurodegenerative Diseases with Oxidative Stress and Nutrition

Vyoma Agarwal
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Abstract

Technology or ease of doing work might be the greatest boon to this era, but it is still a bane for our health and life. Sitting in front of laptops or computers for several hours (sedentary lifestyle), using cell phones, watching television, skipping meals or eating junk/ fast food, lack of physical activities, stress, etc. increase the risk of many lifestyle diseases. All the above-mentioned habits increase the count of free radicals in our body and due to a lack of endogenous and exogenous antioxidants, the body cannot combat oxidative stress. Thus, the chances of occurrence of several chronic diseases like cancer, atherosclerosis, cardiovascular diseases, neurodegenerative diseases, rheumatoid arthritis, chronic inflammations, etc. increase. There are several factors contributing to neurodegeneration of the brain and neurons, in which oxidative stress plays an important role. This review article is the compilation of research done by several other researchers on Neurodegenerative Diseases (NDDs) and is primarily focused on better understanding a few basic questions like the correlation of oxidative stress and nutrition to neurodegeneration, NDDs, their different types, symptoms and causes followed by establishing a relation between oxidative stress and nutrition with the help of several studies carried out by researchers in this context.
神经退行性疾病与氧化应激和营养的相关性
技术或工作的便利可能是这个时代最大的福音,但它仍然是我们健康和生活的祸根。坐在笔记本电脑或电脑前几个小时(久坐的生活方式),使用手机,看电视,不吃饭或吃垃圾/快餐,缺乏体育活动,压力等增加了许多生活方式疾病的风险。上述所有的习惯都增加了我们体内自由基的数量,由于缺乏内源性和外源性抗氧化剂,身体无法对抗氧化应激。因此,癌症、动脉粥样硬化、心血管疾病、神经退行性疾病、类风湿关节炎、慢性炎症等几种慢性疾病的发生机会增加。有几个因素导致大脑和神经元的神经变性,其中氧化应激起着重要作用。这篇综述文章是其他几位研究人员在神经退行性疾病(ndd)方面的研究成果的汇编,主要集中在更好地理解氧化应激和营养与神经退行性疾病、ndd及其不同类型、症状和原因的相关性等几个基本问题,然后通过研究人员在这方面进行的几项研究建立氧化应激和营养之间的关系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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