Application of fluorescent and vibration spectroscopy for septic serum human albumin structure deformation during pathology

Biophotonics-Riga Pub Date : 2017-12-07 DOI:10.1117/12.2295315

A. Zyubin, E. Konstantinova, V. Slezhkin, K. Matveeva, I. Samusev, V. Bryukhanov

引用次数: 0

Abstract

In this paper we perform results of conformational analysis of septic human serum albumin (HSA) carried out by Raman spectroscopy (RS), infrared (IR) spectroscopy and fluorescent spectroscopy. The main vibrational groups were identified and analyzed for septic HSA and its health control. Comparison between Raman and IR results were done. Fluorescent spectral changes of Trp-214 group were analyzed. Application of Raman, IR spectroscopy, fluorescent spectroscopy for conformational changes study of HSA during pathology were shown.

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荧光和振动光谱在脓毒症患者病理过程中血清白蛋白结构变形的应用

本文采用拉曼光谱(RS)、红外光谱(IR)和荧光光谱对脓毒症人血清白蛋白(HSA)进行了构象分析。鉴定并分析了感染性HSA的主要振动群及其健康控制。对拉曼光谱和红外光谱结果进行了比较。分析Trp-214组的荧光光谱变化。介绍了拉曼光谱、红外光谱、荧光光谱在HSA病理过程中构象变化研究中的应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Biophotonics-Riga

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