Role of platelet volume indices in diagnostic approach of thrombocytopenia

Abstract

Background: Platelet indices helps in the diagnosis of myriad cases of thrombocytopenia, the current study was conducted to underline their importance in the diagnosis of thrombocytopenia. Materials and Methods: A prospective cross sectional hospital based study was conducted in the CSSH, Meerut on blood samples received from both OPD and IPD patients from October 2019 to August 2021. A total of 200 cases of thrombocytopenia were studied. Detailed relevant clinical data was recorded including history, physical examination and available investigations including serological results. EDTA sample was run on five part hematology analyzers to collect various Platelet parameters. Results: Among all cases dengue was the main cases of thrombocytopenia . Majority of cases were of destructive thrombocytopenia and showed increased MPV and PDW as compared to hypoproductive thrombocytopenia. Conclusion: The evaluation of thrombocytopenic individuals is necessary in order to determine the cause and its implications for treatment. The interpretation of platelet indices can aid in the initial management of thrombocytopenic patients and avoid unnecessary invasive tests.