Cervical Cancer Elimination by 2030: The “SMASH” Strategy of Raj © A Global Public Health Treatise

R. Rajkumar
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Abstract

Cervical cancer is a leading cancer among women, being the second most gynecological cancers in the developing countries, accounting for about 6 million new cases every year and 3.5 million deaths. The Cervical cancer is easily detectable by simple screening tests, like visual inspection methods, pap smear examination, and the recent HPV DNA test methods. If the precancer conditions are diagnosed, treatment can be done by ablation or excisional methods. The women can be followed by periodic cervical biopsy examinations, ideally once in 6 months for 3 years. If, at the end of 3 years, there is no evidence of cervical precancer, then the women will not develop invasive cancer stages. The HPV vaccination of adult and adolescent girls, offer more than 90% protection against Cervical Cancer. Thus, Cervical cancers are early detectable, effectively treatable and successfully preventable. The author, having been the Principal Investigator for one of the largest Cervical Cancer Screening programs in India, atAmbillikai, Tamil Nadu, India, during 2000–2007, which was in collaboration with the International Agency for Research on Cancer – IARC / WHO. The program was successful in reducing the Incidence Rate of Cervical Cancer by 25% and Mortality Rate due to Cervical Cancer, by 35% in a span of 5 years. From the experiences of this “Proof of Concept” project, the author has advocated, “SMASH” strategy of Raj©, for Cervical Cancer Elimination by 2030, which is deliberated in detail, i n this chapter. Hope that, this will serve as a Global Public Health Treatise, for the health care planners and providers in particular and the community at large, worldwide.
到2030年消除宫颈癌:拉吉的“SMASH”战略©全球公共卫生专著
宫颈癌是妇女的主要癌症,是发展中国家第二大妇科癌症,每年约有600万新病例和350万人死亡。子宫颈癌很容易通过简单的筛查测试发现,如目视检查、巴氏涂片检查和最近的HPV DNA测试方法。如果诊断出癌前病变,可以通过消融或切除的方法进行治疗。妇女可以定期进行宫颈活检检查,理想情况下每6个月一次,持续3年。如果在3年后,没有宫颈癌前期的证据,那么这些妇女就不会发展成侵袭性癌症。成人和少女接种人乳头瘤病毒疫苗可提供90%以上的预防宫颈癌的保护。因此,子宫颈癌可以及早发现、有效治疗和成功预防。作者在2000-2007年期间与国际癌症研究机构(IARC / WHO)合作,在印度泰米尔纳德邦的ambillikai担任印度最大的宫颈癌筛查项目之一的首席研究员。该方案成功地在5年内将宫颈癌发病率降低了25%,将宫颈癌死亡率降低了35%。从这个“概念验证”项目的经验来看,作者提出了Raj©的“SMASH”战略,以实现2030年消除宫颈癌的目标,并在本章中进行了详细的讨论。希望,这将成为全球公共卫生专著,特别是卫生保健计划人员和提供者,以及整个社区,全世界。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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