Evaluation of the Effects of a New Cosmetic Protocol based on the Application of a Home Peel with 1% Retinol

Abstract

Introduction: The main purpose of this study was to determine the safety and tolerance of a new cosmetic procedure based on the use of a Home Peel with 1% retinol. Secondly, the subjective efficacy was evaluated. The treatment was to be considered well-tolerated if it permitted recovery of Trans Epidermal Water Loss (TEWL) within a few days following the procedure and if patients reported no significant adverse effects. This new protocol was to be judged effective if it improved clinical alterations associated with photoaging. Methods: 6 subjects (45 years, Female) with moderate aging were treated with a protocol that included a home peel applied twice daily for 3 days. The protocol included a preparatory and post-procedure period. Pictures to enable clinical evaluation were taken with a Reveal® evice and TEWL was assessed by Tewameter® . The subjective evaluation of the subjects and clinical improvement from the investigator was also registered. Results: A moderate improvement described by both investigator and patients was observed in 83% of subjects. Tolerance was excellent, with low grade of desquamation, erythema and burning sensation after the preparation phase (T0) and immediately following the home peel (T3). Conclusion: A new protocol including a home peel product with retinol demonstrated to be safe and effective in the management of skin aging. Improvement in the signs of aging was perceived by both patients and the investigator, with excellent tolerance.