Biosensor and breast cancer treatment

Abstract

Biosensor based technique for breast cancer treatment uses an encapsulation technique in which biosensor cages radioactive bacteria (Listeria) that are encapsulated within a polymeric membrane (Polycaprolactone). This method is used to deliver targeted therapy to the cancer cell. Biosensor is designed to accommodate antibodies specific to cancer cell's surface marker. When the biosensor comes across these surface markers, complementary binding between antibody and surface marker takes place that leads to the generation of mechanical energy by biosensor. This energy is transmitted to the underlying polymer, so that it ruptures the polymeric membrane, consequently, the radioactive bacteria is released to the site of action, thereby destroying the cancerous cell. This technique prevents the damage of nearby healthy cells that happens in the conventional chemotherapy or radiation therapy.