Case Report: Preliminary Study on Expression of Oxidative Distress in Vaccinated Patients with Anti Sars Cov-2 Vaccine Bnt162b

Abstract

Background: The study aims to investigate oxidative distress in patients vaccinated for Sars COV-2 by comparing them to patients infected with the virus. Case Presentation: The tests carried out on a small population of the female gender showed that the vaccine essentially does not create any oxidative distress unlike Sars COV-2 which instead generates an oxidative storm which, as per literature data, precedes the well-known cytokine storm. We assume that this is due to the different response induced by the vaccine which selectively stimulates lymphocytes without therefore stimulating the activity of macrophages which is instead activated by COVID-19. Conclusion: This study aims to be the starting point for a larger population study that correlates oxidative mechanisms with the vaccine-induced immune response.