UJI EFEKTIVITAS ANTIBAKTERI EKSTRAK DAUN JAMBU BIJI LOKAL (PSIDIUM GUAJAVA L) TERHADAP PERTUMBUHAN STAPHYLOCOCCUS AUREUS DAN BACILUS SUBTILIS SECARA IN VITRO

Abstract

Infectious disease is a disease that affects many Indonesian people. Diarrhea can be caused by bacterial infections of the digestive tract. One treatment for diarrhea traditionally uses natural antibacterial alternatives from plants with. ambu seeds (Psidium guajava) which are thought to be antibiotic. This study aims to determine the antibacterial effectiveness of local guava leaf extract in inhibiting the growth of gastrointestinal pathogenic bacteria (Staphylococcus aureus, Bacilus subtilis) in vitro. The research method is a laboratory experiment with Completely Randomized Design (CRD). Data analysis using the results of the study The largest inhibitory zone diameter of the local guava leaf ethanol extract on the growth of Staphylococcus aureus bacteria at a concentration of 50 mg / ml with an average of 18.5 mm medium zone the biggest inhibition of growth of Bacilus subtilis bacteria at aconcentration of 60 mg / ml with an average diameter of 23.5 mm.