MARKETING STUDY OF ORAL FORMS OF OMEPRAZOLE PREPARATIONS USED FOR THE TREATMENT AND PREVENTION OF GASTROESOPHAGEAL REFLUX DISEASE AND GASTRIC ULCER

L. N. Sheikhmambetova, E. Egorova, E. Bekirova, K. Onishchenko
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Abstract

Some of the most widespread illnesses of alimentary canal are the stomach (gastric) ulcer, duodenal ulcer disease, gastroesophageal reflux diseases. The ethanol of antisecretory treatment of the given acid-dependent diseases are the preparations of the proton pump inhibitor group with omeprazole which is considered to be more effective and investigated. The goal of the research is the oral medications omeprazole (20 mg) assortment market investigation. Materials and methods. The research objects are the State register of medicines data of oral medicinal products including omeprazole dosing 20 mg recorded on the pharmaceutical market as well as the State price register data on the vital medicinal products on April, 4, 2021. Results. According to the SRMP 30 trade names of medicinal products including omeprazole dosing 20 mg as active ingredient in capsules and tablets are registered on the pharmaceutical market in Russian Federation. The omeprazole products distribution in the countries holding registration certificates showed the predominance of domestic production medicinal products (18 trade names, 60 %). The cost analysis of standard daily and course dose oral omeprazole form (20 mg) of different trade names allowed to select economically profitable preparations (”Omeprazole”, LLC “Production of Medicines”, Russia; “Omeprazole”, OJSC ‘‘Synthesis”, Russia; “Omeprazole” LLC BFMP, Russia), the insert of which into the list of medicines to provide the gastroesophageal reflux disease and stomach (gastric) ulcer patients at the regional level is economically feasible as well the medicines with the high price (Losec MUPS AstraZeneca AB, Sweden). Сonclusion. The results of the pharmaceutical market research of oral omeprazole form (20mg) indicates a great majority of generic medicine, a sufficient market capacity, medicine predominance of domestic production (60%).
用于治疗和预防胃食管反流病和胃溃疡的口服奥美拉唑制剂的市场研究
一些最普遍的消化道疾病是胃(胃)溃疡,十二指肠溃疡疾病,胃食管反流疾病。乙醇抗分泌治疗给定的酸依赖性疾病是质子泵抑制剂组与奥美拉唑的制剂,被认为是更有效的和研究。本研究的目的是对口服药物奥美拉唑(20mg)的分类市场进行调查。材料和方法。研究对象是截至2021年4月4日在药品市场上记录的口服药品(包括奥美拉唑20mg)的国家药品注册数据以及重要药品的国家价格注册数据。结果。根据SRMP,在俄罗斯联邦的药品市场上注册了30种药品的商品名,其中包括奥美拉唑,剂量为20毫克,作为胶囊和片剂的有效成分。奥美拉唑产品在持有注册证国家的分布情况显示,国内生产的药品占主导地位(18个商品名,占60%)。标准每日和疗程剂量口服奥美拉唑形式(20mg)的不同商品名允许选择经济上有利可图的制剂的成本分析(“奥美拉唑”,有限责任公司“药品生产”,俄罗斯;“奥美拉唑”,OJSC“合成”,俄罗斯;“奥美拉唑”有限责任公司BFMP,俄罗斯),在区域层面将其纳入提供胃食管反流病和胃(胃)溃疡患者的药物清单,在经济上是可行的,同时也是价格较高的药物(Losec MUPS AstraZeneca AB,瑞典)。Сonclusion。药品市场调研结果表明,口服奥美拉唑剂型(20mg)仿制药占绝大多数,市场容量充足,国产药品占主导地位(60%)。
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