Histological Study on the Diameter of the Acini of the Human Prostate Gland – A Postmortem Study

Abstract

Context: Pathological process in the prostate gland occurs commonly in association with aging and includes inflammation, atrophy, hyperplasia and carcinoma. Detailed histologic knowledge will help urologists and pathologists to adopt appropriate plan for diagnosis and treatment of prostatic disease. Study design: Descriptive type of study. Place and period of study: Department of Anatomy, Dhaka Medical College, Dhaka from August 2006 to June 2007. Materials: 70 post mortem human prostate glands were collected from unclaimed dead bodies that were under examination in the morgue of Department of Forensic Medicine, Dhaka Medical College, Dhaka. Method: The samples were divided into three age groups i.e. group A (10-20 years), group B (21-40 years), group C (41-70 years). Histological study was carried out on relatively 29 fresh samples. Result: The mean ±SD diameter of acini in central zone was 0.29±0.04 mm in group A, 0.40±0.04 mm in group B and 0.43±0.09 mm in group C and the mean±SD diameter of acini in peripheral zone was 0.22±0.02 mm in group A, 0.26±0.05 mm in group B and 0.30±0.06 mm in group C. Statistically significant positive correlation (P<0.001) was found between age and the diameter of acini of the prostate gland. Conclusion: There was change in diameter of prostatic acini in relation to age. Key words: Prostate; histology; acini; diameter. DOI: 10.3329/bja.v8i2.7015 Bangladesh Journal of Anatomy July 2010, Vol. 8 No. 2 pp. 52-55