A Comprehensive Review On Pelletization Technology: A Novel Strategy For Formulation Development

A. Parihar, B. Prajapati, Himanshu Paliwal
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Abstract

Pelletization technology is gaining very much attention in present times as it has provided a competent pathway for the oral drug delivery system manufacturing. Pellets offers many biopharmaceuticals as well as technological recompenses over the conventional dosage forms. Pellets offer required strength for dose which can be blended for the delivery of incompatible bioactive agents and helps in providing different release profiles. In this review we will be discussing the extensively used techniques of pelletization, extrusion and spheronization in detail with their methods and applications in the field of pharmacy as a competent pathway for the novel drug delivery systems.
球团化技术综述:配方开发的新策略
颗粒化技术为口服给药系统的生产提供了一条可行的途径,在目前受到了广泛的关注。颗粒提供了许多生物制药以及技术回报超过传统的剂型。微丸提供所需的剂量强度,可以混合用于不相容的生物活性药物的递送,并有助于提供不同的释放轮廓。在这篇综述中,我们将详细讨论广泛使用的造粒、挤压和滚圆技术及其方法和在药学领域的应用,作为一种新的药物传递系统的有效途径。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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