Medico Legal and Ethical Study of Stem Cell Research in India

K. Srivastava
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Abstract

Stem cells have the ability to produce a large number of specialised cells or tissue by regeneration and differentiation. The cells that regenerate could be known to cure disease or injury. As a result, they are distinguished from other cell types by their ability to replicate themselves. Stem cells offer the potential to develop cell-based therapies. Such type of research could lead to novel and improved treatments for a variety of disorders, including diabetes, spinal cord injuries, Alzheimer's, Parkinson's, and heart disease. Stem cell treatment, also characterized as regenerative medicine, induce the repair mechanism of damaged, diseased, or injured tissue using stem cells and their derivatives. Early-stage embryos are used to obtain human embryonic stem cells. Because human embryonic stem cells are harvested from human embryos, there have been various concerns raised the moral and ethical issues in embryonic stem cell research. On the other hand, reprogramming of somatic cells to make induced pluripotent stem cells, avoids the moral and ethical issues that come with embryonic stem cell research. In human stem cell research in addition to moral issues, informed consent to donate materials, critical downstream research, premature clinical trials and oversight all issues occur. To ensure that stem cell research is carried out in an ethically acceptable way, these ethical and policy issues must be discussed along with scientific challenges. This article examines these challenges and how they are addressed in India are explained.
印度干细胞研究的医学、法律和伦理研究
干细胞具有通过再生和分化产生大量特化细胞或组织的能力。再生的细胞可以治愈疾病或损伤。因此,它们与其他细胞类型的区别在于它们的自我复制能力。干细胞为开发基于细胞的疗法提供了潜力。这种类型的研究可能会导致各种疾病的新颖和改进的治疗方法,包括糖尿病、脊髓损伤、阿尔茨海默病、帕金森病和心脏病。干细胞治疗,也被称为再生医学,利用干细胞及其衍生物诱导受损、病变或受伤组织的修复机制。早期胚胎被用来获得人类胚胎干细胞。由于人类胚胎干细胞是从人类胚胎中获取的,因此在胚胎干细胞研究中出现了各种各样的道德和伦理问题。另一方面,体细胞重编程以制造诱导多能干细胞,避免了胚胎干细胞研究带来的道德和伦理问题。在人类干细胞研究中,除了道德问题,捐赠材料的知情同意、关键的下游研究、过早的临床试验和监督等所有问题都会发生。为了确保干细胞研究以伦理上可接受的方式进行,这些伦理和政策问题必须与科学挑战一起讨论。本文探讨了这些挑战,并解释了如何在印度解决这些挑战。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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