Investigation on the temperature distribution of integrated heater configurations in a Lab-on-a-Chip system

Abstract

Lab-on-a-Chip (LoC) systems offer the opportunity of fast and customized biological analyses executed at the “point-of-need” without expensive lab equipment. Some biological processes need a temperature treatment, therefore a technology platform with an integrated heating functionality has been previously described. It is important to ensure stable and homogeneous thermal conditions for biological reactions in the respective biosensor area. Targeting a good homogeneity of the temperature distribution in the sensor area, the use of multiple heaters is beneficial to control the position and shape of hot spots during heating.