FORMULATION FOR MAKING HAND SANITIZER BASED ON DURIAN PEEL EXTRACT (DURIO ZIBETHINUS MURR) IN IMPROVING ANTIBACTERIAL ABILITY

Margaretta Olivia Br Manik, Jhon Patar Sinurat, Reh Malem Br Karo, R. Berutu
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Abstract

Maceration using ethanol solvent was chosen in extracting durian rind which was then evaporated to obtain 50 grams of durian peel extract. The results of the phytochemical screening test showed that the durian rind contains tannin compounds as evidenced by the addition of Iron (III) chloride reagent to produce a black solution. In addition, durian peel also contains terpenoid compounds which have been proven using the Lieberman Burchard reagent so that a blackish brown ring is produced in the extract. The best hand sanitizer product formulation is 75 mL of 96% ethanol, 2 mL of glycerin, 3 mL of 3% hydrogen peroxide, 10 mL of distilled water and 10 mL of a 6% concentration of durian peel extract solution. The hand sanitizer product has a liquid form, has a clear brownish color, has a distinctive durian rind aroma with a pH around 6 indicating that the hand sanitizer is suitable for use. Concentration of 6% Durian fruit peel hand sanitizer has better antibacterial ability than other concentrations with a large inhibition zone of 12.4 mm which is categorized as a strong level as an antibacterial substance.
以榴莲皮提取物为基础,研制提高抗菌能力的洗手液配方
采用乙醇浸渍法提取榴莲皮,经蒸发可得50克榴莲皮提取物。植物化学筛选试验结果表明,榴莲果皮中含有单宁类化合物,加入氯化铁(III)试剂后得到黑色溶液。此外,榴莲皮还含有萜类化合物,这种化合物已经用Lieberman Burchard试剂证明了,因此在提取物中产生了一个黑褐色的环。最佳的洗手液产品配方为75 mL 96%乙醇、2 mL甘油、3 mL 3%过氧化氢、10 mL蒸馏水和10 mL浓度为6%的榴莲皮提取物溶液。该洗手液产品呈液体状,呈清晰的棕色,有独特的榴莲皮香气,pH值在6左右,表明该洗手液适合使用。浓度为6%的榴莲果皮洗手液抗菌能力较好,抑菌带较大,达12.4 mm,属于强抑菌物质。
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