Effectiveness of the drug the «Ribontel» for the treatments against trematode parasites infecting the fish

Abstract

Diseases caused by Monogenea and Treamentoda are widely distributed among fish in Ukraine's internal reservoirs and cause significant economic losses to the fish industry. The tool "Ribontel" is the development of NSC "IEСVM", in its composition contains the active substance - praziquantel and filler - vermiculite and starch. The purpose of the work is to determine the antiparasitic efficacy of the "Ribontel" agent for the spontaneous invasion of pond fish by the agents Diplostomum spathaceum and Posthodiplostomum cuticola. In experiments, fish that were spontaneously invasive with diplomostomas and post-dipostomostosis were used. In the first experiment, the effectiveness of "Ribontel" was determined when two-year-old Hypophthalmichthys hybrids were infected with the metacarcaras D. spathaceum. Four experimental and control groups of 20 individuals each were formed. Intensity of fish was 13,1 ± 1,0 metacarcaria in one fish. The fish "Ribontel" was given individually per os once: fish of the first experimental group at a dose of 50 mg / kg of weight (by AI), the second - at a dose of 100 mg / kg of weight (by AI), the third - at a dose of 150 mg / kg of mass (by AI), the fourth - at a dose of 200 mg / kg of weight (by AI), the fish of the control group were given a starchy paste without the preparation. After 14 days in fish, the presence of live metacerucaries was determined. According to the results of the research, it was found that the extensiveness and intensive effectiveness of the "Ribontel" means, respectively, 85.0% and 97.8% of the fish in the fourth group, which was prescribed a preparation at a dose of 200 mg / kg of weight (by AI). In the second experiment, the effectiveness of "Ribontel" in the miksinstvazii two-year-old white amour (Ctenopharyngodon idella) metacarcaras D. spathaceum and P. cuticola were determined. Four experimental and control groups of 12 individuals each were formed. The level of intensification by diplostomas was 4.1 ± 0.3 metacarcaries per fish, by post-colostomy from 2.2 ± 0.4 to 2.5 ± 0.4 metatarsarcy per fish. Experiments were carried out according to a scheme similar to the previous experiment. The highest level of intensiveness of the "Ribontel" agent against the agents D. spathaceum and P. cuticola was recorded in fish, which was prescribed 200 mg / kg of the drug (by AI), respectively 92.6% and 90.0%. Consequently, the proposed "Ribontel" agent at a dose of 200 mg / kg of weight (by AI) is effective in controlling the diseases of fish caused by metatarsecary trematodes. The remedy can be introduced into the practice of veterinary medicine for the improvement of fish farms.