Revascularization of immature permanent teeth via blood clot or PRF Platelet rich fibrin: A review

Abstract

Regenerative endodontic procedure in an immature nonvital tooth is a biological treatment approach. Case reports have shown clinical and radiographic success following regenerative procedures and successful continued root development as well as strengthening of the root structure. Even though the primary goal of this treatment is to regenerate functional pulp tissue, a different outcome has been shown in histological analysis. This review discusses the conventional and Platelet rich fibrin (PRF) revascularization and also histological analysis of regenerated tissue in the root canal in animal and human studies.