Analysis of the Applicability of the Picoampere Current Measurement Method Based on an Integrated Amplifier for Recording Ion Current Values

Abstract

The necessity of measuring various parameters in micro and nano channels and pores in microfluidic chips is substantiated. A method for measuring the picoampere current based on an integrated amplifier for recording the values of the ion current is proposed. The design of the measuring device has been developed. Based on the results obtained, the possibility of adapting the proposed method and the developed device for measuring small currents in micro and nano channels of a microfluidic chip is analyzed. The comparison of the data obtained, as well as the analysis of previous results, allowed us to determine the conditions under which it is possible to measure small currents in pores and microchannels with a diameter from 10 nm to 1 micron.