MICROBIAL PATTERN OF DIABETIC FOOT ULCER PATIENT IN JEMURSARI ISLAMIC HOSPITAL SURABAYA PERIOD 2012-2016

A. Donastin, A. Aisyah
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引用次数: 3

Abstract

Diabetic foot ulcers (DFU) are complications in people with diabetes mellitus (DM) in the form of wounds or tissue damage resulting in vascular insufficiency and or neuropathy that can develop into an infection. Early detection of germs of diabetic foot ulcers may be used as a recommendation of empirical therapy before the definitive treatment based on culture results and appropriate antibiotics treatment, which may reduce hospitalization time and amputation events. According to Riskesdas in 2013, state that the number of antibiotic used without prescriptions in Indonesia about 86.1%. The study aims to retrospectively analyze the bacterial culture and drug susceptibility test results for patients with diabetic foot ulcers (DFU) in Jemursari Islamic Hospital Surabaya during 2012–2016 to help clinicians choose a more appropriate empirical antibiotic treatment for DFU. This study used cross–sectional designed with retrospective approaches, which analyzed descriptively and samples were taken by the total sampling of 11 samples. This research was conducted at Islamic Hospital of Jemursari Surabaya in May–September 2017 by using medical record data which are outpatient and inpatients who treatment at Jemursari Islamic Hospital. The result was found 6 types of bacteria consisting of Staphylococcus aureus (18%), Staphylococcus non–haemolytic (18%), Klebsiella pneumonia (27%), Enterobacter aerogenes (18%), Burkholderia cepacia (9%), Escheria coli (9%). The most sensitive antibiotics in the Gram–positive bacteria in this study are Amikacin, Teicoplanin and Oxacillin and the most resistant to Amoxicillin and Ampicillin whereas the most sensitive antibiotics in the Gram–negative bacteria in this study were Meropenem and the most resistant to Ciprofloxacin and Trimethroprim–sulfamethoxazole.
2012-2016年泗水jemursari伊斯兰医院糖尿病足溃疡患者微生物模式分析
糖尿病足溃疡(DFU)是糖尿病(DM)患者的并发症,其形式为伤口或组织损伤,导致血管功能不全和/或神经病变,可发展为感染。糖尿病足溃疡的早期细菌检测可作为经验性治疗的建议,然后根据培养结果和适当的抗生素治疗进行最终治疗,可减少住院时间和截肢事件。根据2013年Riskesdas的数据,在印度尼西亚,未经处方使用抗生素的人数约为86.1%。本研究旨在回顾性分析2012-2016年泗水Jemursari伊斯兰医院(Jemursari Islamic Hospital Surabaya)糖尿病足溃疡(DFU)患者的细菌培养和药敏试验结果,帮助临床医生选择更合适的DFU经验性抗生素治疗方案。本研究采用回顾性的横断面设计,采用描述性分析,共抽样11个样本。本研究于2017年5月至9月在泗水Jemursari伊斯兰医院进行,使用了在Jemursari伊斯兰医院治疗的门诊和住院患者的病历数据。结果共检出6种细菌,分别为金黄色葡萄球菌(18%)、非溶血性葡萄球菌(18%)、肺炎克雷伯菌(27%)、产气肠杆菌(18%)、洋葱伯克霍尔德菌(9%)、大肠杆菌(9%)。本研究革兰氏阳性菌对抗生素最敏感的是阿米卡星、替柯planin和Oxacillin,对阿莫西林和氨苄西林最耐药,而本研究革兰氏阴性菌对抗生素最敏感的是美罗培南,对环丙沙星和甲氧基磺胺恶唑最耐药。
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