Saliency-based image processing for retinal prosthesis

Jianyun Liu, Yuting Zhang, Haiyi Zhu, Leqi Wang, Yanling Han, Yun Zhang, Jing Wang
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Abstract

Retinal prostheses with implantable microelectrodes are proposed for neurogenic retinal diseases that currently do not have effective surgical or medical treatments, such as primary age-related macular degeneration (AMD) and retinitis pigmentosa (RP). It is used to replace damaged neurons and electrically stimulate the remaining intact tissue in the visual pathway. However, due to the current biological and technical limitations, the number of implantable electrodes is limited, and the patient who worn by the device can only perceive a limited discrete light spot (known as artificial vision). The visual perception of the subjects is low-resolution and the external information that the prosthesis could provide is largely lost. Therefore, it is a feasible method to introduce appropriate image processing algorithm in the visual information processing module of the prosthetic device to optimize the information expressed by the phosphene array. So far, many image processing algorithms have been studied under the simulated prosthesis vision of retinal prosthesis. However, most image processing algorithms have complex computational processes, and it takes a long time to process an image. If further applied in prosthesis devices, real-time processing cannot be guaranteed. For retinal prosthesis, this paper proposed a saliency-based image processing algorithm for artificial vision optimization. Based on the global luminance contrast of a captured image, a real-time image processing strategy was proposed to obtain a salient map. The algorithm also combined global luminance contrast features in other color spaces like the RGB and HSI. Meanwhile, this paper proposed a "visual attention simulation processing" model. The model utilized a Gaussian difference model to adaptively extract the most significant regions in the obtained salient map. It can achieve the effect of suppressing the background while enhancing the foreground, thus effectively extracting the foreground in the image. The proposed algorithm was quantitatively and qualitatively evaluated through two open reference image databases of MSRA-10K and ECSSD-1K. Furthermore, the study selected images in the database of frequently used objects for the blind people on the basis of epidemiological data, and simulated the algorithm on the artificial visual simulation experiment platform to verify its feasibility. The evaluation results and experimental results showed that the proposed algorithm was superior to other current algorithms in extracting image saliency information. It not only can process images in real time but also improve the object recognition efficiency under artificial vision condition in the simulation environment. The above research work would provide a theoretical basis for the image processing algorithm of the retinal prosthesis, and would provide an important experimental basis for the postoperative training for visual function rehabilitation of implant patients. This would help the implant patients to reduce potential risks in life and further enhance the implant patients’ independent ability.
基于显著性的视网膜假体图像处理
植入微电极的视网膜假体用于目前没有有效手术或药物治疗的神经源性视网膜疾病,如原发性年龄相关性黄斑变性(AMD)和视网膜色素变性(RP)。它被用来替换受损的神经元,并电刺激视觉通路中剩余的完整组织。然而,由于目前生物和技术的限制,可植入电极的数量有限,佩戴该设备的患者只能感知有限的离散光点(称为人工视觉)。受试者的视觉感知是低分辨率的,并且假体可以提供的外部信息大部分丢失。因此,在假肢装置的视觉信息处理模块中引入合适的图像处理算法,对光幻灯阵列所表达的信息进行优化,是一种可行的方法。目前,人们对视网膜假体模拟视觉下的许多图像处理算法进行了研究。然而,大多数图像处理算法都有复杂的计算过程,处理一幅图像需要很长时间。如果进一步应用于假肢设备,则无法保证实时处理。针对视网膜假体,提出了一种基于显著性的图像处理算法,用于人工视觉优化。基于捕获图像的全局亮度对比,提出了一种实时图像处理策略,以获取显著图。该算法还结合了其他色彩空间(如RGB和HSI)的全局亮度对比特征。同时,提出了“视觉注意模拟加工”模型。该模型利用高斯差分模型自适应提取显著图中最显著的区域。它可以在增强前景的同时达到抑制背景的效果,从而有效地提取图像中的前景。通过两个开放的参考图像数据库MSRA-10K和ECSSD-1K对该算法进行定量和定性评价。此外,本研究在流行病学数据的基础上,从盲人常用物体数据库中选取图像,在人工视觉模拟实验平台上对算法进行仿真,验证算法的可行性。评价结果和实验结果表明,该算法在提取图像显著性信息方面优于现有的其他算法。它不仅可以实时处理图像,而且可以提高仿真环境下人工视觉条件下的目标识别效率。上述研究工作将为视网膜假体的图像处理算法提供理论依据,也将为植入患者的视功能康复术后训练提供重要的实验依据。这将有助于减少种植患者生活中的潜在风险,进一步提高种植患者的独立能力。
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