THE ROLE OF CYTOKINES IN THE DEVELOPMENT OF ARTERIAL HYPERTENSION

Abstract

Arterial hypertension (AH) is a common chronic disease characterized by a persistent increase in blood pressure. In addition to the main mechanisms of hypertension development, including activation of the sympathetic nervous system, disruption of the renin-angiotensin-aldosterone cascade, endothelial dysfunction, increased vascular reactivity, and vascular remodeling, it is assumed that inflammation is also involved in the formation of the disease. The review considers the involvement of cytokines in the pathogenesis of AH, as well as their interaction with blood pressure regulatory systems.