UJI ANTIBAKTERI EKSTRAK ETANOL DAGING BUAH PALA (Myristica Fragrans Houtt.) TERHADAP BAKTERI STAPHYLOCOCCUS AUREUS DAN ESCHERICHIA COLI

Barry Roseveld Joseph Siegers, E. Astuty, Y. Taihuttu
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Abstract

Infectious diseases are still a serious problem in developing countries. Infectious diseases can be treated with antibacterial use. If the irrational use of antibacterials will lead to antibiotic resistance. Nutmeg is a plant that has antibacterial potential. The purpose of this study was to determine the inhibition of the ethanol extract of the nutmeg pulp. The concentrations of the ethanol extract used were 25%, 50%, 75% and 100%. Antibacterial activity test against Staphylococcus aureus and Escherichia coli using the disc diffusion method. The test results showed that all concentrations of ethanol extract had the ability to inhibit the growth of Staphylococcus aureus and Escherichia coli with concentrations of  25%,  50%,  75%  and  100%  with  each  inhibition  zone  for Staphylococcus aureus being 31.4 mm; 36.8 mm; 38.9 mm; 39.1 mm; 43.9 mm, meanwhile Escherichia coli bacteria have an inhibition zone of 14.3 mm; 19.8 mm; 28.9 mm; 32.1 mm; 36.9 mm.
传染病在发展中国家仍然是一个严重的问题。传染病可以用抗菌药物治疗。如果不合理的使用抗菌药会导致抗生素耐药。肉豆蔻是一种具有抗菌潜力的植物。本研究的目的是确定肉豆蔻果肉乙醇提取物的抑制作用。乙醇提取物的浓度分别为25%、50%、75%和100%。圆盘扩散法对金黄色葡萄球菌和大肠杆菌的抑菌活性试验。试验结果表明,各浓度乙醇提取物对金黄色葡萄球菌和大肠杆菌的生长均有抑制作用,浓度分别为25%、50%、75%和100%,对金黄色葡萄球菌的抑制带均为31.4 mm;36.8毫米;38.9毫米;39.1毫米;43.9 mm,大肠杆菌抑菌带14.3 mm;19.8毫米;28.9毫米;32.1毫米;36.9毫米。
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