Antibacterial Activity of Lemongrass Oil and Lemongrass Ethanol Extract Against Porphyromonas gingivalis

Abstract

Objectives: This study analyzed the antibacterial effects of LGEE and LGEO against P. gingivalis, thus the potential utility was evaluated as the functional materials for oral healthcare. Methods: Nitric oxide (NO) assay and cytotoxicity were analyzed by the Griess reaction and WST-1 assay, respectively. Antibacterial activity against P. gingivalis was evaluated by disk diffusion method and proliferation inhibition assay. Results: LGEO and LGEE significantly inhibited NO production as well as the proliferation of P. gingivalis in a dose dependent manner. Conclusions: LGEO and LGEE inhibited potently NO production and P. gingivalis proliferation, which means they could be used as a numerous lines of functional materials for improving oral health.