COVID-19 among Rheumatoid Arthritis Patients on Immunosuppressive Therapy During the First Wave of the COVID-19 Pandemic: a Prospective Comparative Study
{"title":"COVID-19 among Rheumatoid Arthritis Patients on Immunosuppressive Therapy During the First Wave of the COVID-19 Pandemic: a Prospective Comparative Study ","authors":"Amgad Rabia, S. Amer, H. Dawod, Y. Amer","doi":"10.21608/aeji.2022.169271.1262","DOIUrl":null,"url":null,"abstract":"be recruited into three groups: rheumatoid arthritis (RA) patients; rheumatoid arthritis with COVID-19 patients (RA-COVID); and a COVID-19 (COVID-19) group. Results: the mean age of the studied group was 50 years old. The three studied groups showed no statistically significant difference (p > 0.05) as regards age, sex, level of education, and marital status. But there was a statistically significant difference between groups regarding occupation and special habits in the form of hashish smoking. There was no marked difference in COVID-19 symptoms between group II and group III. The mean of the Modified Health Assessment Questionnaire (MHAQ) was 5.5 in RA group versus 8 in RA-COVID-19 group ,with statistically significant difference between group I and II as regard DAS28. The duration from being diagnosed with COVID-19 till recovery was significantly higher in RA-COVID-19 cases compared to COVID-19. RA-COVI-19 group did tend toward higher hospital admission rates (OR 0.81; 95% CI 0.35-0.88; p = 0.03). Conclusion: COVID-19 is accompanied by non-significant worsening of symptoms in RA patients on DMARDs, except the admission rates. More research into expanding cases is required .","PeriodicalId":261891,"journal":{"name":"Afro-Egyptian Journal of Infectious and Endemic Diseases","volume":"121 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Afro-Egyptian Journal of Infectious and Endemic Diseases","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21608/aeji.2022.169271.1262","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
be recruited into three groups: rheumatoid arthritis (RA) patients; rheumatoid arthritis with COVID-19 patients (RA-COVID); and a COVID-19 (COVID-19) group. Results: the mean age of the studied group was 50 years old. The three studied groups showed no statistically significant difference (p > 0.05) as regards age, sex, level of education, and marital status. But there was a statistically significant difference between groups regarding occupation and special habits in the form of hashish smoking. There was no marked difference in COVID-19 symptoms between group II and group III. The mean of the Modified Health Assessment Questionnaire (MHAQ) was 5.5 in RA group versus 8 in RA-COVID-19 group ,with statistically significant difference between group I and II as regard DAS28. The duration from being diagnosed with COVID-19 till recovery was significantly higher in RA-COVID-19 cases compared to COVID-19. RA-COVI-19 group did tend toward higher hospital admission rates (OR 0.81; 95% CI 0.35-0.88; p = 0.03). Conclusion: COVID-19 is accompanied by non-significant worsening of symptoms in RA patients on DMARDs, except the admission rates. More research into expanding cases is required .