COVID-19 among Rheumatoid Arthritis Patients on ‎Immunosuppressive Therapy During the First Wave of the COVID-‎‎19 Pandemic: a Prospective Comparative Study ‎

Amgad Rabia, S. Amer, H. Dawod, Y. Amer
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引用次数: 1

Abstract

be recruited into three groups: rheumatoid arthritis (RA) patients; rheumatoid arthritis with COVID-19 patients (RA-COVID); and a COVID-19 (COVID-19) group. Results: the mean age of the studied group was 50 years old. The three studied groups showed no statistically significant difference (p > 0.05) as regards age, sex, level of education, and marital status. But there was a statistically significant difference between groups regarding occupation and special habits in the form of hashish smoking. There was no marked difference in COVID-19 symptoms between group II and group III. The mean of the Modified Health Assessment Questionnaire (MHAQ) was 5.5 in RA group versus 8 in RA-COVID-19 group ,with statistically significant difference between group I and II as regard DAS28. The duration from being diagnosed with COVID-19 till recovery was significantly higher in RA-COVID-19 cases compared to COVID-19. RA-COVI-19 group did tend toward higher hospital admission rates (OR 0.81; 95% CI 0.35-0.88; p = 0.03). Conclusion: COVID-19 is accompanied by non-significant worsening of symptoms in RA patients on DMARDs, except the admission rates. More research into expanding cases is required .
在第一波COVID-19大流行期间接受免疫抑制治疗的类风湿关节炎患者中的COVID-19:一项前瞻性比较研究
被分为三组:类风湿关节炎(RA)患者;类风湿性关节炎合并COVID-19患者(RA-COVID);新冠肺炎(COVID-19)组。结果:研究组平均年龄50岁。三组患者年龄、性别、文化程度、婚姻状况差异无统计学意义(p < 0.05)。但在职业和吸食大麻的特殊习惯方面,两组之间存在统计学上的显著差异。II组和III组在COVID-19症状方面无显著差异。RA组改良健康评估问卷(MHAQ)的平均值为5.5,RA- covid -19组为8,DAS28在I组和II组之间差异有统计学意义。与COVID-19相比,RA-COVID-19病例从被诊断为COVID-19到康复的持续时间明显更长。ra - cov -19组确实倾向于更高的住院率(OR 0.81;95% ci 0.35-0.88;P = 0.03)。结论:除入院率外,DMARDs治疗的RA患者COVID-19伴症状无明显恶化。需要对不断扩大的病例进行更多的研究。
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