Phototherapy and Synthetic Wound Dressings in the Treatment of Trophic Ulcers of Venous Etiology

Y. Ivanova, E. Klimova, I. Krivoruchko, A. Korobov, Prasol V.A., K.V. Myasoedov
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Abstract

Trophic ulcers are the most difficult and most frequent complication of chronic venous insufficiency of the adult able-bodied population, and is approximately 2%. The study purpose - improvement of the treatment results in patients with chronic venous insufficiency with trophic ulcers due to the use of artificial wound dressings and platelet-rich growth factors and phototherapy. The application of a complex of treatment of trophic ulcers in patients with chronic venous insufficiency, consisting of phototherapy, foamforming of incompetent perforator veins under ultrasound navigation and wound closure with synthetic plaque with a platelet growth factor, is an extremely effective stimulator of development of granulation tissue and spontaneous epithelization of the wound. Promising directions of development of this method of treatment are the studies of cellular mechanisms of regeneration and histological study of the stages of the development of connective tissue under the influence of phototherapy, platelet growth factor and the study of the possibility of using a combination of synthetic coverings and platelet growth factor with vacuum therapy.
光疗与合成创面敷料治疗静脉源性营养性溃疡
营养性溃疡是成年健全人群慢性静脉功能不全最困难和最常见的并发症,约占2%。本研究的目的是利用人工创面敷料、富血小板生长因子及光疗改善慢性静脉功能不全伴营养性溃疡患者的治疗效果。综合治疗慢性静脉功能不全患者的营养性溃疡,包括光疗、超声引导下无功能穿支静脉的泡沫形成和用血小板生长因子合成斑块缝合伤口,是一种非常有效的刺激肉芽组织发育和伤口自发上皮形成的方法。光疗、血小板生长因子影响下结缔组织发育阶段的组织学研究和细胞再生机制的研究,以及合成覆盖物和血小板生长因子结合真空治疗的可能性的研究,是该治疗方法有前景的发展方向。
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