Chronic Musculocutaneous Nerve Injury: An Important Differential in Progressive Arm Atrophy

Umer Younas, Muhammad Tawab Khalil, R. Yasmeen, Omar Shafiq, I. Irshad
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Abstract

An isolated musculocutaneous nerve (MCN) injury is a rare condition that can be easily missed if it presents late. A 28-year-old man reported painless and progressive wasting of the right arm for 6 months. On examination, there was visible wasting of the right biceps brachii muscle along with its slight weakness, depressed biceps jerk, and an impaired pinprick sensation in the lateral antebrachial cutaneous nerve distribution. He described a history of a road traffic accident 14 months beforehand. Based on the history and clinical examination, the differential diagnosis included an isolated MCN injury, upper trunk plexopathy, lateral cord plexopathy, C5/6 radiculopathy, and monomelic amyotrophy involving the C5/6 myotomes on the right side. The results of nerve conduction studies and electromyography were consistent with chronic proximal MCN neuropathy (right). In cases of arm wasting without pain or numbness, MCN injury should be included in the differential diagnosis, even in the presence of good power of the elbow flexors. The importance of detailed history-taking and clinical correlation cannot be over-emphasized in such cases.
慢性肌皮神经损伤:进行性臂萎缩的重要鉴别因素
孤立性肌皮神经(MCN)损伤是一种罕见的疾病,如果出现较晚,很容易被漏诊。一名 28 岁的男子报告说,他的右臂无痛且进行性萎缩已有 6 个月。经检查,他的右臂肱二头肌明显萎缩,并伴有轻微无力、肱二头肌抽动减弱以及肱前皮神经外侧分布的针刺感受损。他描述了 14 个月前的一次道路交通事故史。根据病史和临床检查,鉴别诊断包括孤立的 MCN 损伤、上躯干神经丛病、侧索神经丛病、C5/6 根性神经病和累及右侧 C5/6 肌节的单膜性肌萎缩症。神经传导研究和肌电图结果与慢性 MCN 近端神经病(右侧)一致。在无疼痛或麻木的手臂萎缩病例中,即使肘部屈肌力量良好,也应将 MCN 损伤列入鉴别诊断。在这类病例中,详细询问病史和临床相关性的重要性怎么强调都不为过。
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