[The effect of super-erythematous doses of UV-radiation on the general condition of the human body].

Abstract

The effect of excessive UV-radiation with 2-4, 5-6, or 7-8 minimal erythematous doses (MED) on man's health condition was investigated, when the irradiated surface area made 20% or 50% of the body surface area. Before and 1 or 3 days after exposure the following parameters were measured: skin state, skin perspiration, body temperature, fluid consumption, diuresis, ECG, PCG, occlusion plethysmography. The observations allowed the conclusion that 5-8 MEDs were threshold doses inducing early intoxication in response to local irradiation (20% of the body surface area) and upper body irradiation (50% of the body surface area). Irradiation with 7-8 MEDs caused noticeable intoxication: fever, headache, increased body temperature (37 degrees C and over), inhibited perspiration, fluid retention, and altered cardiac function.