Towards Cardiac Risk Monitoring of Duchene Muscular Dystrophy using Lyfas

Abstract

Duchene Muscular Dystrophy (DMD) is a progressive neuromuscular disorder affecting male children of a career mother, as seen in more than 70% of cases. It is an X-linked recessive disease that affects 1 in 3600-6000 live male births. As the child grows, muscles are progressively wasted and degenerated in the body. As time passes, it also involves intercostal and heart muscles leading to cardiorespiratory failure and death. Using a smartphone-based application namely, Lyfas that uses the principles of the optical sensor, arterial photoplethysmography, and photochromatography, this report focuses on capturing digital cardiovascular biomarkers at the backdrop of DMD and understanding the physiological aspect of the disorder and its progression, especially the risk of the involvement of cardiac muscles.