CNT-Based Nano Medicine From Synthesis to Therapeutic Application

Shabana Yasmeen Ansari, Shoaib Anwar Ansari, Farhan Alshammari, Sirajudheen Anwar
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引用次数: 1

Abstract

Carbon nanotubes (CNTs) are allotropes of carbon consisting of cylindrical tubes, made up of graphite with a diameter of several nm to a length of several mm. They had extraordinary structural, mechanical, and electronic properties due to their small size and mass, high mechanical resilience, and high electrical and thermal conductivity. Their large surface area made them applicable in pharmacy and medicine and adsorb or conjugate a broad variety of medical and diagnostic agents (drugs, genes, vaccines, antibodies, biosensors, etc.). They are often used to deliver drugs directly into the cells without going through the metabolic process of body. In addition to drug delivery and gene therapy, CNTs are also used for tissue regeneration, diagnostic biosensors, chiral drug enantiomer separation, drug extraction, and drug or pollutant analysis. CNTs have recently been discovered as effective antioxidants. The ADME and toxicity of different types of CNTs have also been documented here, as well as the prospects, advantages, and challenges of this promising bio-nano technology.
基于碳纳米管的纳米药物从合成到治疗应用
碳纳米管(Carbon nanotubes, CNTs)是碳的同素异形体,由直径为几纳米到几毫米的石墨组成的圆柱形管。碳纳米管具有体积小、质量好、机械回弹性好、导电性和导热性好等特点,具有优异的结构、机械和电子性能。它们的大表面积使它们适用于药学和医学,并吸附或结合各种医疗和诊断试剂(药物、基因、疫苗、抗体、生物传感器等)。它们通常用于将药物直接输送到细胞中,而不经过身体的代谢过程。除了药物传递和基因治疗外,CNTs还用于组织再生、诊断性生物传感器、手性药物对映体分离、药物提取以及药物或污染物分析。近年来,人们发现碳纳米管是一种有效的抗氧化剂。不同类型碳纳米管的ADME和毒性也被记录在这里,以及这一有前途的生物纳米技术的前景、优势和挑战。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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