Seroprevalence of Hepatitis B, Hepatits C, Human Immunodeficiency Virus and Syphilis in Donated Blood in Kenya, 2016: Situation Analysis

Mahuro Gm, Gichangi Pb, M. Cw, N. Kipkorir
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引用次数: 2

Abstract

Background and Objective: Blood transfusion is a prevalent life-saving intervention that replaces blood or blood-products lost in severe malnutrition, infections, during surgical procedures, obstetrical emergencies and blood disorders or trauma. Transfusion of infected blood remains a public health concern. With all interventions aimed at reducing transfusion transmissible infections (TTIs), it’s imperative to review the Kenyan current situation. This presents TTIs prevalence among volunteer blood donors in Kenya 2016, and, relationship between volunteer blood donors’ health and risk characteristics and TTIs in donated blood. Materials and Methods: This adopts cross-sectional design for data collected for ten months in 2016. Only 17.8% of 20,230 volunteer blood donors recruited through mobile phone application, text for life (T4L), whose blood test results were uploaded into T4L and had complete data on TTI tests was included. Kenya National Blood Transfusion Services pre-screening assessment used prior to voluntary blood donation provided variables of interest for analysis. Descriptive frequencies, association test and odds ratio was performed using Stata V14.2. Result: Four in every five voluntary blood donors were male, and, had no or primary education. Hepatitis B, Hepatitis C, Human immunodeficiency viruses and Syphilis prevalence was 0.7%, 1.2%, 6.2% and 1.0% respectively. Having “disease" or “sexual” does not infer having any TTI but “stab” increases odds of having syphilis two fold (AOR=2.03, 95%CI=0.27-15.15, p=0.000). Conclusion: Excluding individuals who self-report as having had stab wounds could reduce the chances of having TTIs. Individuals found to be having TTIs should receive appropriate referrals for care and support.
2016年肯尼亚捐献血液中乙型肝炎、丙型肝炎、人类免疫缺陷病毒和梅毒的血清阳性率:情况分析
背景和目的:输血是一种普遍的挽救生命的干预措施,可替代在严重营养不良、感染、外科手术、产科急诊和血液疾病或创伤期间流失的血液或血液制品。输血受感染的血液仍然是一个公共卫生问题。所有干预措施都旨在减少输血传播感染(tti),因此必须审查肯尼亚的现状。本文介绍了2016年肯尼亚志愿献血者中tti的患病率,以及志愿献血者的健康和风险特征与捐献血液中tti之间的关系。材料与方法:对2016年10个月的数据采用横断面设计。通过手机应用程序“生命短信”(T4L)招募的20230名志愿献血者中,只有17.8%的人被纳入,他们的血液检测结果被上传到T4L,并具有完整的TTI检测数据。肯尼亚国家输血服务中心在自愿献血之前进行的预筛查评估提供了分析感兴趣的变量。使用Stata V14.2进行描述性频率、关联检验和比值比分析。结果:五分之四的自愿献血者为男性,且未受教育或初等教育。乙型肝炎、丙型肝炎、人类免疫缺陷病毒和梅毒患病率分别为0.7%、1.2%、6.2%和1.0%。有“疾病”或“性行为”并不意味着有任何TTI,但“刺伤”使患梅毒的几率增加两倍(AOR=2.03, 95%CI=0.27-15.15, p=0.000)。结论:排除自我报告有过刀伤的个体可以减少发生tti的机会。被发现患有性传播感染的个人应该接受适当的转诊治疗和支持。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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