Influence of radicality surgical excision on results in the treatment of Basocellular Skin Carcinoma (BCC)

D. Lukic, P. Lazić, Jadran Milos Bandic, Z. Tačević, N. Babić, D. Ivić
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Abstract

With the prospective study, from June 2003 to January 2013, were compared the results of treatment of basocellular carcinomas (BCC) of the skin in 210 respondents. The respondents were divided into 3 groups. The first group, group A (61 respondents) consisted of respondents treated for BCC with surgical excision, with distance incision of 1 cm from the tumor. In the second group, group B (79 respondents) were classified respondents treated for BCC with surgical excision, at distance incision 2 cm from the tumor, while the third group, group C (70 respondents) was classified by respondents treated with surgical excision of BCC, at distance incision approximately 3cm from the tumor. The parameters for comparison of treatment results were: the method (radicality) of treatment, number of the relapse, elapsed time from surgery to relapse and subsequent disfiguration. The aim of this study was to determine the optimal radicality in the treatment of BCC, i.e., the number of relapses in relation to the radicalism of the BCC excisions. In most of the respondents, intraoperative skin defect was closed by direct suture. Spare distance, from the edge of the BCC, which amounts to 1 cm in group A, results in significantly lower percentage of disfigurement. At the same time, in group A was recorded the highest number of recurrences of BCC. Radical surgeries of BCC, which were performed with the resection margin of 3 cm from the BCC, resulted in the lowest number of relapses, but statistically significant percentage of postoperative disfigurement. The most optimal excisional distance from the edge of the BCC is about 2 cm. Due to the significantly smaller number of disfigurement, resections distance of 2 cm from the BCC and direct suture of postoperative defect take precedence, regardless of the localization of the tumor.
根治性手术切除对基底细胞皮肤癌治疗效果的影响
在这项前瞻性研究中,从2003年6月到2013年1月,比较了210名受访者皮肤基底细胞癌(BCC)治疗的结果。受访者被分为三组。第一组,A组(61名应答者)由接受BCC手术切除的应答者组成,切口距离肿瘤1cm。在第二组中,B组(79名)被分类为手术切除BCC的患者,切口距离肿瘤2cm;第三组,C组(70名)被分类为手术切除BCC的患者,切口距离肿瘤约3cm。比较治疗结果的参数为:治疗方法(根治)、复发次数、手术到复发的时间以及随后的毁容。本研究的目的是确定BCC治疗的最佳根治性,即复发的数量与BCC切除的根治性有关。在大多数应答者中,术中皮肤缺损采用直接缝合。A组与基底细胞边缘的距离为1cm,因此毁容率明显降低。同时,A组BCC的复发率最高。BCC根治性手术切除距BCC 3cm,复发率最低,但术后毁容率有统计学意义。最佳切除距离BCC边缘约2cm。由于畸形数量明显较少,无论肿瘤的定位如何,均优先选择距BCC 2 cm的切除和术后缺损的直接缝合。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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