Erythropoietin Response in Patients with Anaemia of Chronic Disorders

Tinuade O. Piwuna, C. Ukoli, Alani S Akanmu
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Abstract

Chronic disease conditions characterized by infection and intense inflammatory response abound in Sub-Saharan Africa and are very often complicated by anemia. Erythropoietin (EPO) is up regulated in response to anemic conditions. In Nigeria there is a dearth of public literature describing Anemia of Chronic Disease (ACD) and Erythropoietin levels in chronic diseases. The aim of the study was to determine the appropriateness of erythropoietin response to anemia observed in chronic disease.
慢性疾病贫血患者的促红细胞生成素反应
在撒哈拉以南非洲,以感染和强烈炎症反应为特征的慢性病比比皆是,而且常常伴有贫血。促红细胞生成素(EPO)在贫血条件下上调。在尼日利亚,缺乏描述慢性病贫血(ACD)和慢性疾病中促红细胞生成素水平的公共文献。该研究的目的是确定红细胞生成素对慢性疾病中观察到的贫血反应的适宜性。
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