A novel gene delivery system using magnetic nanodarts

Abstract

One aspect of gene therapy is the efficient transfection of a cell population with DNAs or RNAs (including siRNAs) in order to modulate the expression of genes, to produce cell types for use in gene therapy, or to meet other very important unmet medical needs. Gene therapy has a huge potential in modifying the blueprints of a human cell and giving additional tools for modern medicine. Gene therapy also offers hope in combating lethal genetic diseases, cancer and certain infectious diseases. According to the report “Meeting the challenge: U.S. Industry faces the 21st century: The U.S. biotechnology industry”, the office of technology policy, U.S. Department of Commerce predicted the growth of this industrial sector to be an estimated $5 Billion within the next decade.