Bacterium with Leuconostoc pseudomesenteroides

L. Iarovoi, T. Holban, Galina Chiriacov, Viorica Cotos, Lilia Cojuhari, Natalia Cirstea
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Abstract

Introduction. Leukonostoc pseudomesenteroides, widespread in nature (soil, plants, milk, etc.), until recently was classified as a commensal microorganism, but from 1985 until now several sporadic cases of infection with this pathogen have been described in humans. Bacteremia with Leuconostoc spp. are increasingly reported. Unique cases of infection of other sites have also been described: in soft, lung, urinary, Central Nervous System tissues, etc. Most often, these cases have been reported in patients with cancer, and are often considered opportunistic for acquired immunodeficiencies. However, several cases have also been reported in immunocompetent patients, including in those previously treated with vancomycin, Leuconostoc spp. having a natural resistance to this antibiotic. Material and methods. An analysis of the literature and the clinical case are presented here: the child of an 11-month-old with congenital malformation - rabbit lip, who underwent maxillofacial operation twice and had pneumonia 2 months before his admission to the Toma Ciorba Infectious Diseases Clinical Hospital. Results. Meningococcemia and meningitis were clinically established upon admission. The blood culture result was received a few days later, and Leuconostoc pseudomesenteroides was identified. The etiological treatment was corrected, after which the sterile result of the blood culture was obtained. The child was released in a satisfactory condition. Conclusions: The clinical case presented is the first case of infection with Leuconstoc spp. described in the Republic of Moldova. The correct choice of the etiological treatment allows the eradication of this pathogen, with a satisfactory clinical result. 
带有假肠球菌的细菌
介绍。假肠杆菌广泛存在于自然界(土壤、植物、牛奶等),直到最近才被归类为共生微生物,但从1985年至今,已有几例人类感染该病原体的散发病例。白菌属菌血症的报道越来越多。其他部位感染的独特病例也有描述:在软,肺,泌尿系统,中枢神经系统组织等。大多数情况下,这些病例报告的是癌症患者,通常被认为是获得性免疫缺陷的机会性。然而,在免疫功能正常的患者中也报告了一些病例,包括以前用万古霉素治疗过的患者,Leuconostoc对这种抗生素具有天然耐药性。材料和方法。本文对文献和临床病例进行分析:一个11个月大的先天性畸形兔唇患儿,在托马·乔巴感染性疾病临床医院入院前2个月接受了两次颌面手术并患肺炎。结果。入院时临床确诊为脑膜炎球菌血症和脑膜炎。几天后接受血培养结果,鉴定为假肠球菌。纠正病原学处理后,获得血培养无菌结果。孩子出院时情况令人满意。结论:提出的临床病例是第一例感染与Leuconstoc spp.描述在摩尔多瓦共和国。病因治疗的正确选择,可以根除这种病原体,取得满意的临床效果。
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