Description of a Hydrogel-Based Micro-Valve As a Library Element for Matlab Simulink

Philipp J. Mehner, Anthony Beck, M. Busek, A. Voigt, U. Marschner, A. Richter
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Abstract

We propose a planar hydrogel-based micro-valve design which is modeled as a library element for Matlab Simulink. For this test case, a pressure pump (voltage source) in series with a micro-valve model (variable fluidic resistance) is built up. The micro-valve subsystem is separated in four main parts. Based on the applied temperature stimulus, the equilibrium length is determined according to an experimentally verified fit function. Furthermore, the equilibrium length considers a static hysteresis effect which is modeled in analogy to the saturation of magnetization in electric transformers. In a second step, the transient behavior follows a first order differential equation, but the cooperate diffusion coefficient is size dependent affecting the rise time of the system. This causes a faster swelling than deswelling of the hydrogel. In the third section, the stiffness property is implemented to calculate the maximum sealing pressure and the resulting gap between the hydrogel and the wall. The fluidic resistance of the micro-valve considers a three-dimensional geometry and is calculated based on a look-up table, extracted from a fluid-structure-interaction (FSI) model generated from a finite element structure. The proposed model allows a full description of the fluidic hydrogel-based micro-valve and is part of an upcoming microfluidic toolbox for Matlab Simulink containing passive elements and optional chemical reactions like mixing fluids and enzyme reactions for future applications.
基于水凝胶的微阀库元件的Matlab Simulink描述
提出了一种基于平面水凝胶的微阀设计方法,并将其建模为Matlab Simulink的库元素。在这个测试案例中,建立了一个带有微阀模型(可变流体阻力)的串联压力泵(电压源)。微阀子系统分为四个主要部分。在施加温度刺激的基础上,根据实验验证的拟合函数确定平衡长度。此外,平衡长度考虑了静态迟滞效应,该效应与变压器中的磁化饱和类似。在第二步中,瞬态行为遵循一阶微分方程,但协同扩散系数与系统上升时间的大小有关。这导致水凝胶的膨胀比膨胀更快。在第三部分中,利用刚度特性计算最大密封压力和水凝胶与壁面之间的间隙。微阀的流体阻力考虑三维几何形状,并基于从有限元结构生成的流固耦合(FSI)模型中提取的查找表进行计算。所提出的模型可以全面描述基于流体水凝胶的微阀,并且是即将推出的Matlab Simulink微流体工具箱的一部分,该工具箱包含被动元件和可选的化学反应,如混合流体和酶反应,以供未来应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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