Differential gene expression in B lymphocyte immune process induced by COVID-19 infection

Abstract

The Sequencing reads of this study are derived from research shared by Aaron J. Wilk. We conducted a deep analysis of B lymphocyte data. A total of 2126 differentially expressed genes were listed out. Through GO enrichment analysis, 24 clusters related to B lymphocyte functioning were screened out, and genes with significant differential expression were mainly enriched in 10 KEGG signaling pathways related to immune regulatory functions. This suggests that there are differences in the expression of immune regulatory genes in the immune process of B lymphocytes during the Sars-Cov2 infection.