A fully implantable and rechargeable neurostimulation system for animal research

Abstract

A neurostimulation system consisting of a reusable, four-channel, fully-implantable rechargeable neurostimulator (INS), recharger and wireless controller is described. The intent of the system is to enable acute and chronic research with stimulation codes and patterns in rodents and large animals as a means to understand the underlying neuroscience principles responsible for neuromodulation therapy, explore improved outcomes for existing therapies and identify potential new therapies. The total volume of the INS is 3cc including the rechargeable battery, stimulation system and low volume lead connector block. Wireless telemetry is inductive and operational with up to 60 cm of separation from the controller so as to enable untethered, real-time program updates.