Effect of Balloon Embedded Bifurcating Stenting with Single Stent Strategy for Side Branch Protection

Bishnu Pada Saha, M. Uddin, S. Hashem, Priyanka Adhikary, Mohammad Arifur Rahman, C. M. K. E Khuda, S. Shahriar, M. Hasan, Mizanur Rahman Majumder, F. Sultana, Whaiduzzaman Jewel
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Abstract

Background: Intervention for bifurcation lesions is associated with increased risk of adverse events and includes acute side branch (SB) occlusion during main branch (MB) stenting. This acute occlusion of side branch can often be catastrophic for the patient. We here in describe our experience in National Institute of Cardiovascular Diseases and Hospital (NICVD), Dhaka, Bangladesh with a technique which can be incorporated into bifurcation stenting to reduce or almost eliminate the incidence of side branch occlusion or catastrophe. Methods: A prospective, observational, non-blinded study in patients from a single tertiary referral cardiac center National Institute of Cardiovascular Diseases & Hospital (NICVD), Dhaka, Bangladesh. Patients with an indication for percutaneous coronary intervention (PCI) of a denovo bifurcation lesion were screened. The study included 51 patients who underwent coronary angiogram in our institution and had bifurcation lesions suitable for single stent strategy between March 2017 to September 2018. Results: 51 patients with bifurcation lesion were included in the study and underwent a balloon embedded bifurcation stenting with a semi inflated balloon placed across the SB ostium. Angiographic success was achieved in all the patients but procedural success was achieved in 88.2% of the patients. TIMI 3 flow of main branch (MB) was achieved 96.08% and side branch (SB) was achieved 88.2%. Incidence of dissection was 5.9%, acute occlusion of SB was 2.0% and MACE was 3.9%. Mean fluoroscopy time and contrast volume was similar to that of conventional bifurcation stenting. The jailed SB balloon and wire could be successfully removed in all patients. Conclusion: The present study suggests that balloon embedded bifurcation stenting with a semi inflated balloon to protect the SB is feasible, with minimal procedural adverse events and successful in minimizing or almost eliminating the incidence of acute side branch occlusion or dissection as well as MACE. Bangladesh Heart Journal 2021; 36(1): 17-23
单支架球囊埋置分岔支架对侧支保护的效果
背景:分叉病变的干预与不良事件的风险增加有关,包括主支(MB)支架置入期间急性侧支(SB)闭塞。这种急性侧支闭塞对病人来说往往是灾难性的。我们在此描述我们在孟加拉国达卡国家心血管疾病和医院研究所(NICVD)的经验,该技术可以纳入分支支架置入,以减少或几乎消除侧支闭塞或灾难的发生率。方法:一项前瞻性、观察性、非盲性研究,研究对象为来自孟加拉国达卡国家心血管疾病与医院研究所(NICVD)单一三级转诊心脏中心的患者。筛选有经皮冠状动脉介入治疗(PCI)指征的患者。本研究纳入了51例2017年3月至2018年9月期间在我院行冠状动脉造影且存在适合单支架治疗的分叉病变的患者。结果:51例分叉病变患者被纳入研究,并接受了球囊埋置分叉支架,半充气球囊放置在SB口。所有患者均获得血管造影成功,但手术成功率为88.2%。主支路(MB)和侧支路(SB)的TIMI 3流量分别达到96.08%和88.2%。夹层发生率为5.9%,急性SB闭塞发生率为2.0%,MACE发生率为3.9%。平均透视时间和造影剂体积与传统支架术相似。在所有患者中,囚禁的SB球囊和金属丝均可成功移除。结论:本研究提示球囊内埋分岔支架采用半充气球囊保护骶椎板是可行的,其手术不良事件最小,成功地减少或几乎消除了急性侧支闭塞或剥离以及MACE的发生率。孟加拉国心脏杂志2021;36 (1): 17-23
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